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There are Several reasons why one tank "consumes" more Ca, the next one more Alk
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Yes, this is especially true when systems have strong algal/macro filters because these try to get carbon from dissolved CO2 in the water. When CO2 can't dissolve into the water fast enough, alk starts being consumed in order to get carbon from it.
The worse case for this is an enclosed algae/chaeto reactor that has no contact with air; it has no choice but to consume alk.